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Germany: New endoscopy technology helps detect esophageal cancer early

Early detection of esophageal cancer thanks to new O2E endoscopy technology, helps improve survival rate up to 90% thanks to high detection accuracy.

VietnamPlusVietnamPlus08/08/2025

German and Austrian researchers have recently developed an advanced imaging technique called "O2E", which allows clinics to detect cancerous lesions in the esophagus with unprecedented accuracy.

According to research published in the journal Nature Biomedical Engineering, this advanced endoscopy technology can detect even the smallest pathological tissue changes, significantly improving the ability to detect and diagnose early.

O2E combines two imaging techniques including OCT which is capable of capturing detailed tissue structures and photoacoustic imaging (OPAM) which can depict even the smallest blood vessels in deeper tissue layers.

By combining these techniques, high-resolution 3D images of tissue structure and function in the esophagus can be created. Both sensors are integrated into an endoscope capsule that is capable of scanning tissue at a 360-degree angle.

Professor Vasilis Ntziachristos, Director of the Institute for Biological and Medical Imaging at Helmholtz Munich and President of the Technical University of Munich (TUM), said the dual imaging system can detect early signs of cancer lesions, including microstructural changes below the mucosal surface and subtle microvascular changes within cancer tissue, which were not detectable by previous methods.

In a pilot study, the researchers examined the esophagus of animals and tissue samples from patients with Barrett's esophagus, a pre-cancerous form of esophageal cancer. They successfully identified distinct differences between healthy tissue, tissue with abnormal, precancerous cell changes, and malignant tumors.

Esophageal cancer is considered one of the most dangerous types of cancer: When diagnosed at an advanced stage, the survival rate is only about 10%. However, if detected early, about 90% of patients can survive./.

(Vietnam News Agency/Vietnam+)

Source: https://www.vietnamplus.vn/duc-cong-nghe-noi-soi-moi-giup-phat-hien-som-ung-thu-thuc-quan-post1054592.vnp


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